Mayo Clinic Staff Meetings: Vascular Clinics. Lipedema of the Legs: A Syndrome Characterized by Fat Legs and Orthostatic Edema
Allen EV, Hines EA; 1940
Synopsis: This article describes the anatomical and physiological basis of lipedema.
Abstract: We wish to describe a clinical syndrome, lipedema of the legs, which is frequently very distressing. In our experience it affects solely women. The chief complaint is of swelling of the legs and feet which has been present for many years; in some instances, first noted in girlhood. On questioning, the physician may elicit that enlargement of the limbs has always been generalized and symmetrical. Usually, it is associated with gradual increase in body weight. There is never a history of recurrent episodes of acute cellulitis such as may occur in the course of lymphedema. The swelling below the knees is accentuated when patients are on their feet much and in warm weather. Aching distress in the legs in common. In many instances, there is a history of a similar condition in other members of the family. Ordinarily, such patients are very sensitive about the appearance of their limbs; they wear long skirts and stand behind chairs when in the presence of strangers. They avoid swimming. Evidence of neurosis is likely to be found. Occasionally, a patient feels that her large legs have “ruined her life”. Many are “ashamed” of their legs.
APA Citation: Allen, E. V., & Hines, E. A. (1940, March). Lipedema of the legs: a syndrome characterized by fat legs and orthostatic edema. In Proc Staff Mayo Clinic,15,184-187.
AMA Citation: Allen EV, Hines EA. Lipedema of the legs: a syndrome characterized by fat legs and orthostatic edema. In Proc Staff Mayo Clinic. 1940 March;15:184-187.