This study evaluated the accuracy of computed tomography (CT) scans in distinguishing lymphedema from deep venous thrombosis (DVT) and lipodystrophy (lipedema).
This article discusses the difficulties lipedema patients face, including misdiagnosis, unresponsiveness to diet and exercise, physical pain, and distress over the appearance of their legs. A case study follows a 21-year old patient with lipedema who was successfully treated with liposuction and compression.
This article presents a series of pedigrees to support the proposition that lipedema is a genetic condition, distinct from obesity and associated with pain, tenderness, and bruising. Lipedema appears to almost exclusively affect females, and is presumably estrogen-requiring, as it often manifests at puberty.