This study evaluated the accuracy of computed tomography (CT) scans in distinguishing lymphedema from deep venous thrombosis (DVT) and lipodystrophy (lipedema).
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This article discusses the difficulties lipedema patients face, including misdiagnosis, unresponsiveness to diet and exercise, physical pain, and distress over the appearance of their legs. A case study follows a 21-year old patient with lipedema who was successfully treated with liposuction and compression.
This article presents a series of pedigrees to support the proposition that lipedema is a genetic condition, distinct from obesity and associated with pain, tenderness, and bruising. Lipedema appears to almost exclusively affect females, and is presumably estrogen-requiring, as it often manifests at puberty.